Osteoporosis is a disease that makes the bone weak and increases the risk of the bone to break. Experts can’t find the reason why bone loss occurs in the HIV positive patient than normal people. HIV, HIV medicines, taking other medicine for a long time, older age is the factors that increase the rate of bone loss. The increased rates of the osteoporosis among HIV infected people are a concern but it is noteworthy that the disease differs from young and middle-aged HIV infected individuals to the older ones. Osteoporosis is less common in men as compared to women.